NAD+, or simply NAD is not a very familiar thing, right? If you studied biochemistry at any point, then you might have heard. And even though you do not know what this molecule, if you watch till the end, then you will realize how big is the impact of NAD on our body.
Nicotinamide Adenine Dinucleotide – N A D is a coenzyme found in all living cells. It plays a crucial role in various biological processes, including energy metabolism, DNA repair, and gene expression. It acts as an electron carrier, accepting electrons from other molecules during metabolic reactions. These electrons are then transferred to other molecules, such as the electron transport chain in mitochondria, where they participate in generating ATP. Additionally, NAD serves as a substrate for enzymes involved in DNA repair processes and plays a role in regulating gene expression through enzymes called sirtuins, which require NAD as a cofactor. NAD levels have been implicated in various aspects of health and ageing, and there is ongoing research into potential therapeutic interventions targeting NAD metabolism.
Is it too much information to digest? Guess not. Okay, now, let’s see some of these benefits of NAD.
10 Health Benefits of NAD
Anti-Aging
NAD levels tend to decline with age, and this decline has been implicated in various aspects of ageing, including decreased mitochondrial function, impaired DNA repair, and altered gene expression. Some research suggests that boosting NAD levels through supplementation may help mitigate these age-related changes and potentially promote healthy ageing and longevity. That is why NAD is more popular as an anti-ageing treatment.
Now comes the question of how to use it and where to find it. That is why before moving on to the other potential benefits, we are going to discuss more about its origin and availability.
NAD can be obtained from various sources, both from dietary intake and through endogenous synthesis within the body. Certain foods contain precursors or compounds that can be converted into NAD in the body. Niacin or vitamin B3 is a precursor to NAD synthesis in the body. So, poultry, fish, beef, peanuts, mushrooms, and whole grains are good options. Nicotinamide riboside or nicotinamide mononucleotide is also directly involved in the production of NAD in the body. While milk and Yeast are good sources of them, they are also available as supplements which are marketed to increase NAD levels.
Some medical procedures, such as intravenous NAD therapy, involve direct administration of NAD to patients. This method is sometimes used for certain medical conditions or as part of anti-ageing or wellness treatments. However, the efficacy and safety of these therapies are subject to ongoing research and debate.
With that note, let’s see what this list has to reveal.
Energy Enhancement
NAD plays a crucial role in energy metabolism by participating in cellular respiration, where it helps convert nutrients into ATP, the primary energy currency of cells. Some individuals may take NAD supplements to support energy levels, especially if they experience fatigue or have conditions that affect energy metabolism. It can help improve cellular energy production, supporting overall energy levels and stamina.
Physical Performance
Athletes and fitness enthusiasts may seek NAD therapy to enhance physical performance, improve muscle recovery, and increase endurance. It can help optimize cellular energy metabolism and support muscle function. It can aid in muscle development and post-workout recovery. It can also support achieving restful sleep by enhancing energy production and combating fatigue, leading to a more rejuvenating sleep experience which in turn boosts energy, fitness, and performance.
Fighting Chronic diseases
NAD therapy may complement conventional treatments for various chronic health conditions, including autoimmune disorders, cardiovascular diseases, chronic pain conditions, and inflammatory conditions. A big example is how NAD help to fight diabetes. It is found that boosting NAD levels is related to improved insulin sensitivity and secretion, potentially reducing the risk of metabolic disorders like diabetes and its precursors. NAD can assist in weight loss by boosting metabolism, curbing cravings, and improving mood, complementing a healthy lifestyle. Weight matching your age and height is always a good indicator of health and it helps to stay away from illnesses.
Neurological Health
NAD is also involved in various processes within the brain, including neuronal signaling, neuroprotection, and neurotransmitter synthesis. It also protects neurons from oxidative stress, potentially benefiting individuals with neurodegenerative diseases and preserving cognitive function with age. Some individuals may take NAD supplements or undergo NAD therapy in the hope of supporting brain health and potentially reducing the risk of conditions such as Alzheimer’s disease and Parkinson’s disease.
You might be having doubts about the NAD therapy we mentioned. That is why you need this explanation of how one can take NAD as a treatment.
There are a few types of NAD therapies and they have their own delivery methods.
NAD can also be taken orally in the form of supplements such as capsules or tablets. However, NAD is not readily absorbed through the digestive system due to its large molecular size and susceptibility to degradation. To address this issue, some supplements contain precursors to NAD, such as nicotinamide riboside or nicotinamide mononucleotide and they will be converted into NAD within the body.
There are also topical formulations of NAD available in the form of creams or gels that can be applied to the skin. These formulations are typically used for localized effects, such as improving skin health or reducing inflammation in specific areas.
Some NAD therapies involve using a nasal spray to deliver NAD directly into the nasal passages. This method bypasses the digestive system and allows for rapid absorption into the bloodstream.
Intravenous or IV NAD therapy involves administering NAD directly into the bloodstream through an IV drip. This method allows for rapid absorption and higher bioavailability compared to other delivery methods. IV therapy is often preferred for its effectiveness and quick onset of action. If you are suspicious about the IV therapy, NAD can also be administered as an intramuscular or IM injection. This method involves injecting NAD directly into the muscle tissue, allowing for efficient absorption into the bloodstream.
It is always recommended to get professional advice on when and how to get NAD therapies and whether you really need the therapy. As we already mentioned, you can always opt for dietary options which will help you increase the NAD levels in your blood.
Whether you take NAD in a therapy form or boost your NAD through food, it can always give you the benefits. And, our list is not over yet.
Addiction Recovery
Using NAD has shown promise in supporting addiction recovery by reducing cravings, alleviating withdrawal symptoms, and promoting detoxification. It is shown to aid individuals undergoing treatment for substance abuse, including alcohol, drugs, and even addictive behaviours like gambling.
Combat Mood Disorders
Science says that NAD therapy can benefit individuals struggling with mood disorders like depression, anxiety, and bipolar disorder. It can help rebalance neurotransmitter levels such as serotonin, promote neuroplasticity, and improve emotional well-being.
Metabolic Health
NAD can play a role in improving metabolic health by enhancing insulin sensitivity, regulating blood sugar levels, and supporting weight management. It may be beneficial for individuals with metabolic disorders such as diabetes, obesity, or metabolic syndrome.
Skin Health
NAD therapy may contribute to healthier skin by promoting collagen production, reducing oxidative stress, and improving cellular regeneration. It may help alleviate signs of ageing, such as wrinkles, fine lines, and uneven skin tone.
Detoxification
It is also known that NAD can support detoxification processes within the body by enhancing cellular repair mechanisms, reducing oxidative stress, and promoting the elimination of toxins. It may be beneficial for individuals undergoing detox programs or seeking to improve overall health. NAD supplementation also provides an energy boost, making daily tasks more manageable and enjoyable. Hence, you can have a freshen-up, toxic-free day.
Now you know so much about NAD and we hope it helped you learn a lot. It’s important to note that while NAD therapy shows promise for these indications, more research is needed to fully understand its efficacy and safety in different populations and contexts. And, as with many supplements, how one’s body reacts to NAD can be subjective and use it after proper consultation.
